Dietary Insights and Nutritional Education in Adults on GLP-1 Therapy (DINE-GLP1) Study

GLP-1 medications, like Ozempic, Wegovy, or Mounjaro, are increasingly prescribed to help manage weight and type 2 diabetes. They work by reducing appetite and helping people feel full, which can lead to significant weight loss. But long-term improvements in health often require ongoing changes to diet and lifestyle.

 

The DINE-GLP1 study explores how people’s eating habits and overall health change while taking GLP-1 medications, and how we can best support healthy dietary habits. People on GLP-1 medications might not be eating a high-quality diet so the aim of the DINE-GLP1 program is to help you eat the right foods while you lose weight. Note that the GLP-1 medication itself is not the focus of this study. Participants will use their medication as prescribed by their healthcare provider.

 

Are you currently taking GLP-1 medication? Complete our eligibility screener to see if you qualify for our 6-week mobile Nutritional Education intervention.

Learn More

Participate

If you have been prescribed a GLP-1 medication and have been taking it for at least 4 weeks, you can join this 6-week study. We will examine changes in your diet and experiences with the GLP-1 medication before and after a 6-week mobile health (mHealth) intervention aiming to help you improve the quality of your diet. You will also be invited to a single 30-minute interview about your experience with GLP-1 and the mHealth intervention. We want to learn how easy or challenging it was to take the GLP-1 medication, any side effects, and how the mHealth program was helpful in supporting your healthy eating. Complete our eligibility screener to see if you qualify.

Eligibility

Participants must meet the following criteria in order to participate:

  • Are 18-65 years old
  • Have a BMI between 30-49.9kg/m2 or have been diagnosed with type 2 diabetes without major complications
  • Are currently prescribed a GLP-1 medication and have been on the medication for at least 4 weeks
  • Not pregnant or planning on becoming pregnant during the study and also not breastfeeding.
  • Own a smartphone with internet access
  • Live anywhere in the United States
  • Have access to a digital body weight scale to record your weight before and after the intervention

Meeting these eligibility criteria is essential for participating in the DINE-GLP1 Study. If you fulfill these requirements and are ready to embrace positive changes in your diet, we encourage you to take the eligibility survey.

Study Timeline

  • Eligibility Survey
  • Eligibility Interview & Orientation
  • Baseline Assessment (after at least 4 weeks on GLP-1 medication)
    • Current medications
    • Reported weight
    • Diet assessment
  • Training Online Meeting
  • Start SWITCH Diets Intervention (6 weeks)
    • Continue GLP-1 medication during this period
  • End-of-Study Assessment (6 weeks after starting SWITCH Diets, while continuing GLP-1)
    • Current medications
    • Reported weight
    • Diet assessment
    • Structured interview
Graphic of study timeline

Remember:

  • This study does not test the GLP-1 medication itself.
  • You must enroll once you have completed at least 4 weeks of taking your prescribed GLP-1.

Key Features of the DINE-GLP1 Study

Research lead and conducted by researchers at the University of South Carolina, at the Behavioral Research in Eating Lab (About | BRIE Lab):  We research innovative ways to help people eat healthier, lose weight, and prevent chronic disease using emerging technologies and dietary approaches. Our work explores health, digital self-monitoring, and nutrient-rich  diets to support lasting health behavior change.

Convenient Remote Participation:  Join from the comfort of your home. No in-person visits are required.

Intervention: Immerse yourself in an engaging and interactive 6-week intervention delivered seamlessly through the SWITCH app. Experience a dynamic online environment that fosters active participation and encourages positive behavior change.

Targeted Audience: We are seeking approximately 50 adult volunteers with obesity and/or type 2 diabetes (T2DM) who are currently taking GLP-1 medications for at least the past 4 weeks.

Incentives

As a token of our appreciation, participants will receive up to $50 in gift cards for completing their end of the study assessment.

Ready to Get Started?

If this opportunity aligns with your interests,  If you fulfill these requirements and are ready to embrace positive changes in your diet, we encourage you to take the eligibility screener. We'll reach out to you within two weeks regarding your eligibility.
Join us on the journey to better health with the DINE-GLP1 Study – where positive diet changes begin online!

Contact us

For any additional information or clarification, feel free to reach out to our study coordinator, Dr. Carolina Delgado-Diaz, delgadoc@mailbox.sc.edu.